Interactor 1: PLCG1 (P19174)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Interactor 2: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 17474147
Identification Methods fluorescence technology, peptide array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_2, Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1290
Hs

1 1731
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs

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Last updated: 15 Jul 2024