HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: SCFD1 (Q8WVM8)
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Gene: SCFD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 642
+	Hs
		988565 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		953589 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		1015634 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		955420 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		962321 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		125731 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		988747 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		125708 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		125710 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		581314 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		125726 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		125733 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		125727 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		953697 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		125728 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		STXB3_HUMAN (9-641): 2.85e-155: 461: 16.54
+	Hs
		1015829 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		955651 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		962535 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		VPS45_HUMAN (38-640): 9.77e-154: 456: 20.66
+	Hs
		1015770 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		VP33B_HUMAN (3-639): 2.09e-111: 349: 13.40
+	Hs
		955576 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		VP33B_HUMAN (3-639): 2.09e-111: 349: 13.40