HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: BAIP2 (Q6GMN2)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase substrate protein p53)
Gene: Baiap2

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	32357304
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0010976 - positive regulation of neuron projection development GO:0030182 - neuron differentiation GO:0043005 - neuron projection and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 535
+	Rn
		94244 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		BAIP2_RAT (1-535): 3.83e-151: 445: 100.00
+	Hs
		497821 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		BAIP2_HUMAN (1-529): 6.96e-143: 424: 94.52
+	Hs
		497550 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PACN1_HUMAN (13-436): 2.09e-85: 273: 14.19
+	Rn
		555250 TAU_RAT (1-752): 2.4e-95: 314: 100.00		SPTN1_RAT (6-443): 1.22e-51: 192: 14.29
+	Rn
		94140 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		SPTN1_RAT (6-443): 1.22e-51: 192: 14.29
+	Hs
		497800 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PACN2_HUMAN (13-437): 1.01e-71: 238: 17.57
+	Mm
		498047 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		PACN1_MOUSE (13-436): 4.09e-56: 196: 13.76
+	Hs
		496988 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		SPTN1_HUMAN (6-443): 2.52e-50: 188: 14.29
+	Hs
		203251 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		PACN1_HUMAN (13-436): 2.09e-85: 273: 14.19
+	Hs
		965102 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		SPTN1_HUMAN (6-443): 2.52e-50: 188: 14.29
+	Mm
		561172 ANK2_MOUSE (184-606): 1.18e-23: 109: 16.21		SPTN1_MOUSE (6-443): 1.9e-51: 191: 14.29
+	Hs
		203262 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		PACN2_HUMAN (13-437): 1.01e-71: 238: 17.57
+	Hs
		203224 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		MYO1E_HUMAN (50-436): 1.87e-46: 176: 11.90
+	Hs
		1349277 DAPLE_HUMAN (3-620): 7.14e-32: 135: 10.16		ITSN2_HUMAN (237-434): 3.64e-10: 65: 15.00
+	Hs
		203260 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		PACN3_HUMAN (13-312): 2.23e-23: 104: 11.08
+	Hs
		203228 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		ITSN1_HUMAN (357-458): 8.72e-10: 64: 18.63