HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: S39A1 (Q9NY26)
Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zinc-iron-regulated transporter-like) (Zrt- and Irt-like protein 1) (ZIP-1) (hZIP1)
Gene: SLC39A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 324
+	Mm
		626856 TNR1A_MOUSE (1-445): 4.25e-127: 377: 64.37		S39A7_MOUSE (38-323): 6.84e-57: 192: 18.13
+	Hs
		639629 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		S39AD_HUMAN (31-322): 1.93e-57: 191: 19.41
+	Hs
		639619 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		S39A7_HUMAN (38-323): 1.88e-54: 186: 18.07
+	Hs
		1266224 TR10D_HUMAN (38-345): 3.39e-33: 130: 15.85		S39A7_HUMAN (38-323): 1.88e-54: 186: 18.07
+	Hs
		639609 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		S39AB_HUMAN (52-319): 5.01e-33: 126: 19.23
+	Hs
		645798 CD27_HUMAN (42-281): 3.74e-29: 116: 16.87		S39A6_HUMAN (167-323): 4e-43: 159: 15.48
+	Hs
		989760 TNR9_HUMAN (56-221): 5.56e-20: 90.8: 16.87		S39AA_HUMAN (135-323): 2.3e-48: 174: 19.02
+	Hs
		989745 TNR9_HUMAN (56-221): 5.56e-20: 90.8: 16.87		S39A6_HUMAN (167-323): 4e-43: 159: 15.48