HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 337
+	Hs
		258831 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		DNJA2_HUMAN (2-336): 2.58e-119: 351: 31.46
+	Hs
		987999 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		DJB11_HUMAN (2-334): 1.07e-98: 297: 31.34
+	Hs
		258721 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		DNJA2_HUMAN (2-336): 2.58e-119: 351: 31.46
+	Hs
		439969 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		DNJA1_HUMAN (5-335): 1.05e-117: 347: 32.46
+	Hs
		258873 PTK6_HUMAN (4-141): 7.17e-23: 97.1: 38.93		DNJA2_HUMAN (2-336): 2.58e-119: 351: 31.46
+	Hs
		727711 CSK_HUMAN (2-139): 3.94e-24: 100: 36.24		DNJA1_HUMAN (5-335): 1.05e-117: 347: 32.46
+	Hs
		727800 PTK6_HUMAN (4-141): 7.17e-23: 97.1: 38.93		DNJA1_HUMAN (5-335): 1.05e-117: 347: 32.46
+	Hs
		258749 VAV_HUMAN (2-60): 7.9e-14: 71.6: 42.37		DNJA2_HUMAN (2-336): 2.58e-119: 351: 31.46
+	Hs
		584484 VAV_HUMAN (2-60): 7.9e-14: 71.6: 42.37		DNJA1_HUMAN (5-335): 1.05e-117: 347: 32.46
+	Hs
		258896 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		DNJA2_HUMAN (2-336): 2.58e-119: 351: 31.46
+	Hs
		1154187 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		DJB11_HUMAN (2-334): 1.07e-98: 297: 31.34