HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: MCCA (Q96RQ3)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)
Gene: MCCC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25609649
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 725
+	Hs
		398223 NFKB1_HUMAN (1-968): 0: 796: 100.00		PCCA_HUMAN (1-715): 0: 649: 37.38
+	Hs
		587551 NFKB1_HUMAN (1-968): 0: 796: 100.00		ACACA_HUMAN (29-725): 0: 609: 25.40
+	Hs
		513530 NFKB1_HUMAN (1-968): 0: 796: 100.00		PYC_HUMAN (47-707): 0: 601: 33.04
+	Hs
		135965 ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82		ACACB_HUMAN (24-723): 0: 578: 26.01
+	Hs
		653228 RELB_HUMAN (30-459): 1.19e-121: 384: 33.10		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76
+	Hs
		653233 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76
+	Hs
		653213 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76
+	Hs
		121570 IKBE_HUMAN (541-751): 2.35e-29: 125: 38.07		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76
+	Hs
		653227 NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76
+	Hs
		653377 Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41		PYR1_HUMAN (6-467): 1.37e-72: 259: 15.76