Interactor 1: PRP4 (P20053)
U4/U6 small nuclear ribonucleoprotein PRP4 (Pre-mRNA-processing protein 4)
Gene: PRP4

Interactor 2: PRP3 (Q03338)
U4/U6 small nuclear ribonucleoprotein PRP3 (Pre-mRNA-splicing factor 3)
Gene: PRP3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 9826507, 11283351, 11805826, 16429126, 18719252, 37968396, 14759368
Identification Methods affinity chromatography technology, two hybrid pooling approach, two hybrid, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRP3~WD40, DUF1115~WD40
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005687 - U4 snRNP
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 465
Sc

1 469
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024