Interactor 1: ODPX (P16451)
Pyruvate dehydrogenase complex protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (Pyruvate dehydrogenase complex component E3BP)
Gene: PDX1

Interactor 2: ODPX (P16451)
Pyruvate dehydrogenase complex protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (Pyruvate dehydrogenase complex component E3BP)
Gene: PDX1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19523954
Identification Methods cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_lipoyl~Biotin_lipoyl
Common GO terms GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity
GO:0005198 - structural molecule activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 410
Sc

1 410
+ Sc
+ Ce
+ Mm
+ At
+ Mm
+ At
+ Zm
+ Ss
+ Sc
+ Hs
+ At
+ At
+ Ec
+ Mm
+ Sc
+ At

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Last updated: 11Aug2025