HitPredict

Interactor 1: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Interactor 2: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	18467557, 37968396
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 576 Sc			1 1729
+	Hs
		903230 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058048 NLE1_HUMAN (407-558): 2.17e-27: 117: 13.75		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058065 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058000 SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		672800 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		CDC27_HUMAN (1106-1729): 6.38e-66: 243: 12.30
+	Hs
		672926 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		CDC27_HUMAN (1106-1729): 6.38e-66: 243: 12.30
+	Mm
		56871 FZR1_MOUSE (337-559): 1.97e-22: 102: 16.96		CDC27_MOUSE (1106-1729): 2.94e-65: 241: 12.03
+	Dm
		571971 Q9VPL0_DROME (324-565): 3.68e-38: 145: 12.10		CRN_DROME (1245-1728): 7.77e-41: 164: 11.59
+	Hs
		174768 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		175177 TBL1R_HUMAN (321-561): 3.43e-27: 117: 12.55		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		174868 PWP1_HUMAN (331-554): 4.52e-20: 95.6: 9.49		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		174829 RBBP4_HUMAN (330-523): 4.94e-20: 94.6: 15.05		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		1318163 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		CRNL1_HUMAN (1208-1729): 7.73e-38: 156: 11.75
+	Ce
		185194 LIN53_CAEEL (330-523): 1.2e-19: 93.4: 16.10		OGT1_CAEEL (1280-1684): 7.93e-35: 147: 10.41
+	Hs
		300095 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		1288293 SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34		CRNL1_HUMAN (1208-1729): 7.73e-38: 156: 11.75
+	Hs
		300287 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		300229 SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		1288323 SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34		SYF1_HUMAN (1511-1727): 3.02e-18: 93.6: 12.31