HitPredict

Interactor 1: TA2R (P21731)
Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)
Gene: TBXA2R

Interactor 2: GNA13 (Q14344)
Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)
Gene: GNA13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 10318854, 8290554, 15782186, 10488151, 12399457
Identification Methods biochemical, affinity chromatography technology, fluorescent resonance energy transfer, pull down
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~G-alpha
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 - positive regulation of cytosolic calcium ion concentration
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 343
Hs

1 377
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024