HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: MPP7 (Q5T2T1)
MAGUK p55 subfamily member 7
Gene: MPP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0030010 - establishment of cell polarity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 576
+	Hs
		1212209 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		MPP7_HUMAN (1-576): 3.78e-175: 509: 100.00
+	Hs
		988429 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		MPP7_HUMAN (1-576): 3.78e-175: 509: 100.00
+	Hs
		1015503 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		MPP7_HUMAN (1-576): 3.78e-175: 509: 100.00
+	Hs
		581096 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		MPP7_HUMAN (1-576): 3.78e-175: 509: 100.00
+	Hs
		962140 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		MPP7_HUMAN (1-576): 3.78e-175: 509: 100.00
+	Hs
		168748 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		CSKP_HUMAN (1-575): 7.99e-138: 425: 30.17
+	Hs
		168631 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		CSKP_HUMAN (1-575): 7.99e-138: 425: 30.17
+	Hs
		168669 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		CSKP_HUMAN (1-575): 7.99e-138: 425: 30.17
+	Hs
		168672 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		CSKP_HUMAN (1-575): 7.99e-138: 425: 30.17
+	Hs
		168627 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		CSKP_HUMAN (1-575): 7.99e-138: 425: 30.17
+	Hs
		962263 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		PALS1_HUMAN (3-574): 3.56e-131: 400: 35.95
+	Hs
		1091569 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29
+	Hs
		601396 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		DLG3_HUMAN (6-371): 3.53e-27: 118: 12.31
+	Hs
		601260 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29
+	Hs
		1015652 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		DLG3_HUMAN (6-371): 3.53e-27: 118: 12.31
+	Hs
		988325 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29
+	Mm
		988891 RAC1_MOUSE (10-195): 2.03e-80: 239: 63.98		DLG4_MOUSE (94-485): 3.1e-22: 103: 11.97
+	Hs
		1015397 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29
+	Hs
		581014 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29
+	Hs
		961999 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		DLG1_HUMAN (2-228): 2.16e-23: 106: 14.29