HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: RUFY3 (Q7L099)
Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)
Gene: RUFY3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RUN~Ras
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 469
+	Hs
		601416 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		988637 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		1095589 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		1015703 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		581249 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		962412 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		601264 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		988329 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		1015404 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		581017 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		773156 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		MYH10_HUMAN (249-467): 4.92e-42: 162: 15.53
+	Hs
		962005 RHOA_HUMAN (1-201): 1.72e-76: 229: 49.75		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		953419 RAC3_HUMAN (10-183): 3.69e-76: 228: 66.67		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		955113 CDC42_HUMAN (9-193): 3.18e-75: 226: 67.57		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		977974 RHOB_HUMAN (1-204): 2.53e-75: 226: 49.51		LIPA1_HUMAN (52-469): 7.73e-43: 164: 15.28
+	Hs
		773143 CDC42_HUMAN (9-193): 3.18e-75: 226: 67.57		MYH10_HUMAN (249-467): 4.92e-42: 162: 15.53
+	Hs
		772724 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		MYH9_HUMAN (236-467): 2.44e-34: 139: 15.09
+	Hs
		772743 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		MYH9_HUMAN (236-467): 2.44e-34: 139: 15.09
+	Hs
		581189 RAC2_HUMAN (10-196): 9.52e-77: 230: 62.03		SNX29_HUMAN (68-232): 2.35e-32: 132: 23.63
+	Hs
		978188 RHOB_HUMAN (1-204): 2.53e-75: 226: 49.51		SNX29_HUMAN (68-232): 2.35e-32: 132: 23.63