Interactor 1: SDHB (P21801)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)
Gene: SDH2

Interactor 2: SDHA (Q00711)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (FP)
Gene: SDH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 37968396, 32051233, 23043141, 16429126
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_2~Fer2_3, Fer2_3~Succ_DH_flav_C, FAD_binding_2~Fer4_17
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
GO:0008177 - succinate dehydrogenase (quinone) activity
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 266
Sc

1 640
+ Sc
+ Hs
+ Ec
+ Hp
+ Ec
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024