Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.951

The method score is based on:

Property Details
Experiments 12887919, 10830168, 11069186, 19060208, 9700203, 22726438
Identification Methods pull down, x-ray crystallography, protein kinase assay, blue native page, fluorescent resonance energy transfer
Interaction Type direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, Ig_3~I-set, Ig_3~Ig_3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001657 - ureteric bud development
GO:0001701 - in utero embryonic development
GO:0001837 - epithelial to mesenchymal transition
and 108 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 821
Hs

1 821
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Last updated: 15 Jul 2024