HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0030010 - establishment of cell polarity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 214
+	Hs
		988553 PARD3_HUMAN (1-1356): 0: 706: 100.00		RAC1_HUMAN (22-214): 5.21e-81: 241: 58.03
+	Hs
		601386 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHOQ_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		978190 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		962307 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHOA_HUMAN (23-214): 3.34e-78: 234: 47.92
+	Hs
		1015627 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHOG_HUMAN (20-214): 6.8e-78: 233: 50.26
+	Hs
		581191 PARD3_HUMAN (1-1356): 0: 706: 100.00		RAC2_HUMAN (22-214): 1.82e-77: 232: 57.51
+	Hs
		466378 PARD3_HUMAN (1-1356): 0: 706: 100.00		RHOC_HUMAN (23-214): 2.17e-76: 229: 48.44
+	Hs
		953580 PARD3_HUMAN (1-1356): 0: 706: 100.00		RAC3_HUMAN (22-195): 2.77e-76: 229: 62.64
+	Hs
		955407 PARD3_HUMAN (1-1356): 0: 706: 100.00		CDC42_HUMAN (20-214): 2.17e-76: 229: 61.03
+	Hs
		978191 PAR3L_HUMAN (1-1353): 6.79e-109: 374: 33.38		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		962308 PAR3L_HUMAN (1-1353): 6.79e-109: 374: 33.38		RHOA_HUMAN (23-214): 3.34e-78: 234: 47.92
+	Hs
		466379 PAR3L_HUMAN (1-1353): 6.79e-109: 374: 33.38		RHOC_HUMAN (23-214): 2.17e-76: 229: 48.44
+	Dm
		828067 X2JFU8_DROME (1-1082): 3.36e-77: 283: 21.87		CDC42_DROME (20-204): 9.95e-84: 248: 63.64
+	Hs
		601396 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		RHOQ_HUMAN (17-213): 1.34e-80: 240: 78.00
+	Hs
		978210 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		RHOB_HUMAN (23-214): 1.85e-80: 240: 48.44
+	Hs
		962343 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		RHOA_HUMAN (23-214): 3.34e-78: 234: 47.92
+	Hs
		1015652 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		RHOG_HUMAN (20-214): 6.8e-78: 233: 50.26
+	Hs
		953602 DLG3_HUMAN (556-1119): 1.07e-27: 123: 13.64		RAC3_HUMAN (22-195): 2.77e-76: 229: 62.64
+	Mm
		988891 DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98		RAC1_MOUSE (22-214): 5.21e-81: 241: 58.03
+	Mm
		1189508 DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98		Q3TLP8_MOUSE (22-214): 3.64e-76: 229: 52.36