HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 28514442, 33961781, 23972473
Identification Methods affinity chromatography technology, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, Ig_3~I-set, Ig_3~Ig_3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0003416 - endochondral bone growth
GO:0004713 - protein tyrosine kinase activity
GO:0005007 - fibroblast growth factor receptor activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 821
Hs

1 806
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024