Protein: ALS2
Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)

Gene: ALS2
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q96Q42

Gene Ontology (top 5):
GO:0001662 - behavioral fear response
GO:0001726 - ruffle
GO:0001881 - receptor recycling
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

730166

1433B
14-3-3 protein beta/alpha

7

20

High-throughput

0.745

High

966770

1433G
14-3-3 protein gamma

4

20

High-throughput

0.697

High

990627

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.697

High

1049688

1433F
14-3-3 protein eta

4

20

High-throughput

0.697

High

1222163

AL2CL
ALS2 C-terminal-like protein

1

5

High-throughput

0.691

High

1349266

WDR20
WD repeat-containing protein 20

1

7

High-throughput

0.691

High

691351

1433T
14-3-3 protein theta

4

20

High-throughput

0.687

High

1400534

KTU
Protein kintoun

3

2

High-throughput

0.667

High

228922

CF410
Cilia- and flagella-associated protein 410

2

6

High-throughput

0.628

High

971903

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.628

High

1339577

STXB6
Syntaxin-binding protein 6

2

1

High-throughput

0.628

High

1400363

NEK1
Serine/threonine-protein kinase Nek1

2

8

High-throughput

0.628

High

631420

RAB5A
Ras-related protein Rab-5A

1

6

Small-scale

0.618

High

988623

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

Small-scale

0.618

High

1400531

ALS2
Alsin

1

17

Small-scale

0.618

High

1400535

DJB11
DnaJ homolog subfamily B member 11

2

3

High-throughput

0.601

High

914021

CHIO
Beta-chimaerin

2

8

High-throughput

0.571

High

1400533

PDC10
Programmed cell death protein 10

2

0

High-throughput

0.547

High

1005495

RBM6
RNA-binding protein 6

1

4

High-throughput

0.536

High

1387818

ATG4C
Cysteine protease ATG4C

1

0

High-throughput

0.513

High

586987

CHIN
N-chimaerin

1

5

High-throughput

0.479

High

935026

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

1156187

ZYX
Zyxin

1

5

High-throughput

0.479

High

1158484

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.479

High

1231864

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.479

High

1255138

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

593192

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

1031508

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.458

High

1258551

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

559001

LYL1
Protein lyl-1

1

3

High-throughput

0.437

High

1395380

NEUL4
Neuralized-like protein 4

1

2

High-throughput

0.407

High

1400532

SDF2
Stromal cell-derived factor 2

2

0

High-throughput

0.328

High

1259061

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025