HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: AP1B1 (P36000)
AP-1 complex subunit beta-1 (Beta-1-adaptin) (Clathrin assembly protein complex 1 beta-1 large chain) (Clathrin assembly protein large beta-1 chain)
Gene: APL2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	10564262, 11489214
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 726
+	Hs
		925852 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2B1_HUMAN (21-726): 0: 636: 34.41
+	Hs
		960765 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1B1_HUMAN (21-726): 0: 630: 35.79
+	Rn
		509763 CLH1_RAT (4-1648): 0: 2901: 49.76		AP2B1_RAT (21-726): 0: 636: 34.41
+	Hs
		212619 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1G1_HUMAN (3-720): 0: 555: 13.89
+	Hs
		321529 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A1_HUMAN (5-726): 3.05e-168: 510: 14.08
+	Mm
		567504 CLH1_MOUSE (4-1648): 0: 2909: 49.82		AP2A1_MOUSE (5-726): 1.67e-167: 508: 14.19
+	Hs
		302138 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A2_HUMAN (5-683): 3.93e-157: 480: 14.31
+	Hs
		960775 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP3B2_HUMAN (29-637): 1.38e-147: 459: 20.99
+	At
		1012804 CLAH1_ARATH (2-1642): 0: 2628: 43.39		APBLB_ARATH (21-701): 0: 568: 36.30
+	Sc
		604359 CLH_YEAST (1-1653): 0: 2506: 100.00		AP2B_YEAST (43-602): 5.91e-166: 496: 25.21
+	Dm
		669566 CLH_DROME (4-1650): 0: 2804: 48.58		COPB_DROME (19-479): 3.9e-24: 110: 14.67