HitPredict

Interactor 1: EGL10 (P49809)
Regulator of G-protein signaling egl-10 (Egg-laying defective protein 10)
Gene: egl-10

Interactor 2: GBB2 (Q20636)
Guanine nucleotide-binding protein subunit beta-2
Gene: gpb-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 11333232, 12354761
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007212 - G protein-coupled dopamine receptor signaling pathway
GO:0007631 - feeding behavior
GO:0008277 - regulation of G protein-coupled receptor signaling pathway
GO:0046662 - regulation of egg-laying behavior
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 555
Ce

1 369
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Bt
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025