HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: AP1G1 (Q12028)
AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin)
Gene: APL4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	11489214, 18467557
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Alpha_adaptinC2~Clathrin
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 832
+	Hs
		212619 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1G1_HUMAN (3-831): 0: 638: 28.59
+	Hs
		302138 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A2_HUMAN (5-831): 0: 558: 17.07
+	Hs
		321529 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2A1_HUMAN (5-831): 0: 549: 17.37
+	Mm
		567504 CLH1_MOUSE (4-1648): 0: 2909: 49.82		AP2A1_MOUSE (5-831): 1e-180: 547: 17.26
+	Hs
		960765 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP1B1_HUMAN (26-827): 7.24e-171: 520: 13.35
+	Hs
		925852 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP2B1_HUMAN (26-827): 1.36e-167: 511: 12.55
+	Rn
		509763 CLH1_RAT (4-1648): 0: 2901: 49.76		AP2B1_RAT (26-827): 1.36e-167: 511: 12.55
+	Hs
		150206 CLH1_HUMAN (4-1648): 0: 2909: 49.76		AP3D1_HUMAN (4-735): 1.42e-147: 465: 18.43
+	At
		1012804 CLAH1_ARATH (2-1642): 0: 2628: 43.39		APBLB_ARATH (26-830): 2.12e-155: 478: 13.53