Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: GP161 (Q8N6U8)
G-protein coupled receptor 161 (G-protein coupled receptor RE2)
Gene: GPR161

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 28514442, 33961781, 32707033, 23455922
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Pkinase
Common GO terms GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 351
Hs

1 529
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025