Interactor 1: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: IRAK2 (Q8CFA1)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (mu-IRAK-2)
Gene: IRAK2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 30108181, 22011580, 24529375
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0008063 - Toll signaling pathway
GO:0031663 - lipopolysaccharide-mediated signaling pathway
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Mm

1 622
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024