Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL
Interactor 2: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.71 | 1.00 | 0.845 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Cbl_N~UQ_con, UBA~UQ_con, UQ_con~zf-C3HC4 |
Common GO terms | GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006511 - ubiquitin-dependent protein catabolic process and 4 others more... |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024