HitPredict

Interactor 1: TCEA1 (P23193)
Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o)
Gene: TCEA1

Interactor 2: LEO1 (Q8WVC0)
RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein)
Gene: LEO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	37696373, 20178742
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 666
+	Hs
		274708 TCEA3_HUMAN (2-301): 2.74e-105: 312: 51.59		LEO1_HUMAN (1-658): 3.68e-123: 382: 100.00
+	Sc
		425467 TFS2_YEAST (3-300): 8.07e-76: 235: 31.85		LEO1_YEAST (212-666): 3.22e-39: 152: 19.40