HitPredict

Interactor 1: SP100 (P23497)
Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa)
Gene: SP100

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 879 Hs			1 136
+	Hs
		727874 SOX6_HUMAN (506-843): 1.88e-50: 193: 11.93		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		263429 DEAF1_HUMAN (446-716): 1.15e-39: 157: 18.12		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		449665 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		449674 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		449756 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		175769 HMGB3_HUMAN (675-855): 1.68e-34: 132: 54.70		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		935035 HMGB4_HUMAN (675-862): 2.77e-34: 131: 29.79		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		175771 HMGB3_HUMAN (675-855): 1.68e-34: 132: 54.70		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		934695 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952293 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		952739 SSRP1_MOUSE (642-837): 3.39e-29: 126: 21.65		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		996726 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		643320 HMGB2_HUMAN (675-861): 3.05e-30: 120: 63.10		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		643324 HMGB2_HUMAN (675-861): 3.05e-30: 120: 63.10		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		643360 HMGB2_HUMAN (675-861): 3.05e-30: 120: 63.10		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952276 TFAM_HUMAN (683-859): 1.46e-29: 120: 18.18		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		643358 HMGB2_HUMAN (675-861): 3.05e-30: 120: 63.10		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		449604 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		828208 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		643268 HMGB2_HUMAN (675-861): 3.05e-30: 120: 63.10		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00