Protein: TRIB1
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)

Gene: TRIB1
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q96RU8

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004860 - protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1324361

STK40
Serine/threonine-protein kinase 40

5

19

High-throughput

0.930

High

1363535

TRIB2
Tribbles homolog 2

2

17

High-throughput

0.811

High

1340786

COP1
E3 ubiquitin-protein ligase COP1

8

11

Small-scale

0.755

High

316628

ST17B
Serine/threonine-protein kinase 17B

1

19

High-throughput

0.691

High

1157880

DDB1
DNA damage-binding protein 1

1

5

High-throughput

0.691

High

1181532

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

8

High-throughput

0.691

High

1272665

DET1
DET1 homolog

3

3

High-throughput

0.675

High

584135

FOSL2
Fos-related antigen 2

3

17

High-throughput

0.667

High

909380

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

6

High-throughput

0.628

High

1402072

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

2

3

High-throughput

0.628

High

1402073

PECR
Peroxisomal trans-2-enoyl-CoA reductase

2

1

High-throughput

0.628

High

1402078

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

2

4

High-throughput

0.628

High

887148

CEBPA
CCAAT/enhancer-binding protein alpha

2

9

Small-scale

0.619

High

370762

FOS
Protein c-Fos

2

15

High-throughput

0.618

High

853903

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

18

Small-scale

0.618

High

1038343

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

19

Small-scale

0.618

High

1402071

TRIB1
Tribbles homolog 1

1

15

Small-scale

0.575

High

607019

CEBPB
CCAAT/enhancer-binding protein beta

2

11

Small-scale

0.545

High

66548

TSPY2
Testis-specific Y-encoded protein 2

1

3

High-throughput

0.536

High

252971

PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

1

10

High-throughput

0.536

High

584041

FOSL1
Fos-related antigen 1

1

15

High-throughput

0.536

High

603681

JUNB
Transcription factor JunB

1

8

High-throughput

0.536

High

617338

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

15

High-throughput

0.536

High

921055

FOSB
Protein FosB

1

14

High-throughput

0.536

High

1126747

BECN1
Beclin-1

1

1

High-throughput

0.536

High

1146336

L2GL1
Lethal(2) giant larvae protein homolog 1

1

3

High-throughput

0.536

High

1402074

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1402079

HSPB8
Heat shock protein beta-8

1

7

High-throughput

0.536

High

1121645

MORC3
MORC family CW-type zinc finger protein 3

1

0

High-throughput

0.513

High

1402077

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.513

High

611579

LOX12
Polyunsaturated fatty acid lipoxygenase ALOX12

1

4

Small-scale

0.508

High

1094244

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.501

High

1325514

FBXW8
F-box/WD repeat-containing protein 8

1

9

Small-scale

0.501

High

945908

INHBE
Inhibin beta E chain

1

1

High-throughput

0.489

High

1062183

PCDH1
Protocadherin-1

1

5

High-throughput

0.489

High

1402075

KLC2
Kinesin light chain 2

1

2

Small-scale

0.481

High

1402076

MLXPL
Carbohydrate-responsive element-binding protein

1

3

Small-scale

0.479

High

887458

CEBPD
CCAAT/enhancer-binding protein delta

1

16

Small-scale

0.408

High

1152988

CEBPE
CCAAT/enhancer-binding protein epsilon

1

14

Small-scale

0.408

High

1340408

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025