Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21731497
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0043065 - positive regulation of apoptotic process
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 424
Mm

1 464
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024