Protein: JAM1
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)

Gene: JAM1, F11R
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9Y624

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001817 - regulation of cytokine production
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376154

RASK
GTPase KRas

4

20

High-throughput

0.873

High

375051

RASH
GTPase HRas

3

20

High-throughput

0.827

High

1058966

ZO1
Tight junction protein 1

2

20

Small-scale

0.821

High

894451

MMP14
Matrix metalloproteinase-14

2

2

High-throughput

0.783

High

168777

CSKP
Peripheral plasma membrane protein CASK

2

13

Small-scale

0.777

High

948975

CD81
CD81 antigen

2

13

Small-scale

0.776

High

374309

RASN
GTPase NRas

2

20

High-throughput

0.754

High

1448410

PICK1
PRKCA-binding protein

4

5

Small-scale

0.702

High

902409

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

12

High-throughput

0.691

High

1214391

SYT6
Synaptotagmin-6

1

4

High-throughput

0.691

High

1286491

DSG4
Desmoglein-4

1

15

High-throughput

0.691

High

1353687

LRC15
Leucine-rich repeat-containing protein 15

1

15

High-throughput

0.691

High

1417705

TX101
Testis-expressed protein 101

1

2

High-throughput

0.691

High

226922

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

5

10

High-throughput

0.661

High

1307685

ZDH17
Palmitoyltransferase ZDHHC17

1

11

High-throughput

0.618

High

1491752

WIF1
Wnt inhibitory factor 1

1

14

High-throughput

0.618

High

341184

DIRA3
GTP-binding protein Di-Ras3

1

10

High-throughput

0.618

High

556448

CADH1
Cadherin-1

1

14

High-throughput

0.618

High

774737

BASI
Basigin

1

18

High-throughput

0.618

High

956560

RAB2A
Ras-related protein Rab-2A

1

17

High-throughput

0.618

High

978434

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1051347

KPCZ
Protein kinase C zeta type

1

5

Small-scale

0.618

High

1145200

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1491799

JAM1
Junctional adhesion molecule A

1

14

High-throughput

0.618

High

1210138

SNP47
Synaptosomal-associated protein 47

2

1

High-throughput

0.606

High

1411170

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

7

High-throughput

0.606

High

1453945

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

5

High-throughput

0.606

High

1228791

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.602

High

1353314

PARD3
Partitioning defective 3 homolog

2

20

Small-scale

0.595

High

660306

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.584

High

1007423

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.580

High

1402486

MYADM
Myeloid-associated differentiation marker

2

0

High-throughput

0.580

High

1415457

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

1450226

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

1460204

PRAF1
Prenylated Rab acceptor protein 1

2

0

High-throughput

0.580

High

1353744

MOT10
Monocarboxylate transporter 10

1

7

High-throughput

0.575

High

936499

AFAD
Afadin

1

20

Small-scale

0.561

High

878728

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

2

1

High-throughput

0.553

High

1490768

NTNG1
Netrin-G1

1

4

High-throughput

0.536

High

828479

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.518

High

1098699

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

274825

DNJB6
DnaJ homolog subfamily B member 6

1

9

High-throughput

0.489

High

1252019

STAC2
SH3 and cysteine-rich domain-containing protein 2

1

12

High-throughput

0.489

High

975348

ARF6
ADP-ribosylation factor 6

1

12

High-throughput

0.479

High

1430663

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1365714

LAR4B
La-related protein 4B

1

3

High-throughput

0.470

High

1453936

TM216
Transmembrane protein 216

1

1

High-throughput

0.437

High

712739

IL12A
Interleukin-12 subunit alpha

2

0

High-throughput

0.328

High

1328232

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

1328827

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1459980

PGAP2
Acyltransferase PGAP2

2

0

High-throughput

0.316

High

1446328

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.279

Low

516287

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

1414833

MTNA
Methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.268

Low

1445923

AMBN
Ameloblastin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025