Interactor 1: RAE1 (P24386)
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)
Gene: CHM

Interactor 2: PGTA (Q92696)
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
Gene: RABGGTA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 35271311, 28514442, 33961781, 21905166
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GDI~PPTA
Common GO terms GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0007601 - visual perception
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 653
Hs

1 567
+ Hs
+ Dm
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024