HitPredict

Interactor 1: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Interactor 2: TAF5 (P38129)
SAGA complex/transcription factor TFIID complex subunit TAF5 (TAFII-90) (TBP-associated factor 5) (TBP-associated factor 90 kDa) (Transcription initiation factor TFIID subunit 5)
Gene: TAF5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.80	0.714

Property	Details
Experiments	11805837, 21734642
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 572 Sc			1 798
+	Hs
		209325 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		PRP4_HUMAN (278-766): 1.3e-87: 288: 20.43
+	Hs
		209218 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		PRP4_HUMAN (278-766): 1.3e-87: 288: 20.43
+	Hs
		882051 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		POC1B_HUMAN (326-643): 4.64e-64: 223: 17.08
+	Hs
		1407594 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		NLE1_HUMAN (600-798): 1.04e-53: 195: 26.79
+	Hs
		1407533 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		TBL1Y_HUMAN (56-596): 4.47e-53: 194: 13.80
+	Mm
		989457 CH60_MOUSE (4-556): 0: 525: 54.20		A16L1_MOUSE (252-795): 4.07e-37: 149: 17.14
+	Mm
		1009925 TCPH_MOUSE (11-569): 0: 524: 18.07		A16L1_MOUSE (252-795): 4.07e-37: 149: 17.14
+	Hs
		532430 CH60_HUMAN (4-556): 5.39e-180: 521: 54.38		LIS1_HUMAN (53-496): 1.76e-37: 147: 10.49
+	Hs
		532666 CH60_HUMAN (4-556): 5.39e-180: 521: 54.38		A16L1_HUMAN (289-795): 1.12e-35: 145: 16.89
+	Hs
		1227340 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		A16L1_HUMAN (289-795): 1.12e-35: 145: 16.89
+	Hs
		845257 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		LIS1_HUMAN (53-496): 1.76e-37: 147: 10.49
+	Hs
		881975 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		A16L1_HUMAN (289-795): 1.12e-35: 145: 16.89
+	Hs
		1407542 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		KTNB1_HUMAN (479-721): 2.84e-24: 110: 26.34
+	Hs
		1334162 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		POC1A_HUMAN (256-496): 7.36e-16: 82.5: 9.02
+	Hs
		532498 CH60_HUMAN (4-556): 5.39e-180: 521: 54.38		WDR5_HUMAN (313-494): 7.95e-12: 69.4: 8.56
+	Hs
		1291941 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		WDR5B_HUMAN (222-493): 3.68e-13: 73.2: 7.02
+	Hs
		965190 TCPH_HUMAN (11-559): 1.17e-177: 514: 18.04		WDR5_HUMAN (313-494): 7.95e-12: 69.4: 8.56
+	Hs
		882038 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		POC1A_HUMAN (256-496): 7.36e-16: 82.5: 9.02
+	Hs
		882014 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		WDR5B_HUMAN (222-493): 3.68e-13: 73.2: 7.02
+	Hs
		881861 TCPG_HUMAN (10-568): 3.05e-172: 500: 14.46		WDR5_HUMAN (313-494): 7.95e-12: 69.4: 8.56