HitPredict

Interactor 1: TBAL3 (A6NHL2)
Tubulin alpha chain-like 3 (EC 3.6.5.-)
Gene: TUBAL3

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 465
+	Hs
		227132 TBA1B_HUMAN (1-443): 0: 688: 74.04		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228503 TBA1C_HUMAN (1-444): 0: 687: 73.20		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227858 TBA1A_HUMAN (1-443): 0: 685: 73.82		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228556 TBB2B_HUMAN (1-445): 0: 685: 38.65		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227133 TBA4A_HUMAN (1-443): 0: 681: 73.59		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227134 TBB4B_HUMAN (1-444): 0: 668: 38.74		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228902 TBA8_HUMAN (1-443): 0: 668: 71.56		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		62743 TBAL3_HUMAN (1-446): 0: 947: 100.00		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		226284 TBB5_HUMAN (1-445): 0: 667: 38.43		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Dm
		1098189 TBB1_DROME (1-445): 0: 689: 38.43		Q9VT94_DROME (194-464): 9.94e-67: 224: 21.46
+	Hs
		1348225 TBA8_HUMAN (1-443): 0: 668: 71.56		ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67
+	Hs
		312567 TBA1B_HUMAN (1-443): 0: 688: 74.04		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312568 TBB4B_HUMAN (1-444): 0: 668: 38.74		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312449 TBB5_HUMAN (1-445): 0: 667: 38.43		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		475961 TBA1A_HUMAN (1-443): 0: 685: 73.82		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475606 TBA4A_HUMAN (1-443): 0: 681: 73.59		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		668104 TBA6_ARATH (1-442): 0: 647: 66.82		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1013212 TBA4_ARATH (1-442): 0: 646: 66.82		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17