HitPredict

Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 808 Hs			1 522
+	Hs
		1055665 MCM6_HUMAN (2-800): 0: 688: 26.50		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		709132 MCM7_HUMAN (10-669): 0: 650: 31.62		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		627356 MCM3_HUMAN (1-808): 0: 944: 100.00		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		832455 MCM2_HUMAN (10-721): 0: 707: 30.62		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		708903 MCM7_HUMAN (10-669): 0: 650: 31.62		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		536740 MCM7_HUMAN (10-669): 0: 650: 31.62		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		708975 MCM7_HUMAN (10-669): 0: 650: 31.62		LNX2_HUMAN (58-183): 1.56e-11: 69.1: 21.88