Protein: LRC8B
Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)

Gene: LRC8B, LRRC8B
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q6P9F7

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0015810 - aspartate transmembrane transport
GO:0034702 - monoatomic ion channel complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1243374

LRC8A
Volume-regulated anion channel subunit LRRC8A

5

13

Small-scale

0.919

High

1243375

LRC8C
Volume-regulated anion channel subunit LRRC8C

4

13

High-throughput

0.892

High

1237937

LRC8E
Volume-regulated anion channel subunit LRRC8E

3

19

High-throughput

0.855

High

1243371

LRC8D
Volume-regulated anion channel subunit LRRC8D

3

13

High-throughput

0.855

High

935679

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.656

High

252686

TSN3
Tetraspanin-3

2

3

High-throughput

0.628

High

1243378

LMBR1
Limb region 1 protein homolog

2

2

High-throughput

0.628

High

1243379

CTL1
Choline transporter-like protein 1

2

3

High-throughput

0.628

High

1243380

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

2

2

High-throughput

0.628

High

1243381

TM2D3
TM2 domain-containing protein 3

2

1

High-throughput

0.628

High

1195348

ANO6
Anoctamin-6

2

0

High-throughput

0.602

High

1243373

T179B
Transmembrane protein 179B

2

0

High-throughput

0.602

High

1243377

CHPT1
Cholinephosphotransferase 1

2

0

High-throughput

0.602

High

1243383

ABCB9
ABC-type oligopeptide transporter ABCB9

2

0

High-throughput

0.602

High

228090

PM34
Peroxisomal membrane protein PMP34

2

1

High-throughput

0.574

High

1243385

SGT1
Protein SGT1 homolog

2

20

High-throughput

0.574

High

560977

GP1BB
Platelet glycoprotein Ib beta chain

1

6

High-throughput

0.536

High

938577

PSA
Puromycin-sensitive aminopeptidase

1

4

High-throughput

0.536

High

1243382

TTYH1
Protein tweety homolog 1

1

4

High-throughput

0.536

High

1243386

RHBD3
Rhomboid domain-containing protein 3

1

2

High-throughput

0.489

High

129188

MEN1
Menin

1

1

High-throughput

0.479

High

1035707

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

1113429

CUL3
Cullin-3

1

10

Small-scale

0.479

High

1243376

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1243384

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

618263

CADH2
Cadherin-2

1

4

High-throughput

0.445

High

76544

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

14

High-throughput

0.437

High

1103550

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

0

High-throughput

0.328

High

1216905

TM164
Transmembrane protein 164

2

0

High-throughput

0.328

High

1243372

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

2

0

High-throughput

0.328

High

665619

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025