Interactor 1: IF2B (P20042)
Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF2-beta)
Gene: EIF2S2
Interactor 2: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311, 35031321, 28524877, 38334954, 31839598, 26186194, 28514442, 33961781, 35235311, 37071682, 36652389, 39422127, 40437099, 16288713 |
| Identification Methods | affinity chromatography technology, cross-linking study, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GTP_EFTU~eIF-5_eIF-2B |
| Common GO terms | GO:0001731 - formation of translation preinitiation complex GO:0002183 - cytoplasmic translational initiation GO:0003743 - translation initiation factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
