Protein: IF2B
Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF2-beta)

Gene: IF2B, eIF2beta
Organism: Drosophila melanogaster
Interactions: 83
UniProt ID: P41375

Gene Ontology (top 5):
GO:0001731 - formation of translation preinitiation complex
GO:0002183 - cytoplasmic translational initiation
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834848

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

2

1

High-throughput

0.571

High

834885

IF5
Eukaryotic translation initiation factor 5

2

3

Small-scale

0.571

High

834871

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.547

High

55413

A1Z9E3
Elongation factor Tu

1

1

High-throughput

0.514

High

834841

Q0E931
GTP-binding protein 1

1

3

High-throughput

0.514

High

834872

LIX1
Protein limb expression 1 homolog

1

0

High-throughput

0.486

High

834875

PKRA
Protein krasavietz

1

7

Small-scale

0.479

High

55672

A1Z9J2
Short stop, isoform C

1

0

Small-scale

0.458

High

654216

DDX6
ATP-dependent RNA helicase me31b

1

3

High-throughput

0.445

High

834834

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.445

High

834837

POLO
Serine/threonine-protein kinase polo

1

1

High-throughput

0.445

High

834838

KC1A
Casein kinase I isoform alpha

1

2

High-throughput

0.445

High

834843

SARM1
NAD(+) hydrolase sarm1

1

1

High-throughput

0.445

High

834847

Q7KMQ0
26S proteasome regulatory subunit 7

1

2

High-throughput

0.445

High

834860

Q9V3V6
26S proteasome regulatory complex subunit p50

1

4

High-throughput

0.445

High

834850

Q7KV95
Purine nucleoside phosphorylase

1

1

High-throughput

0.439

High

52644

A1Z729
NADP-retinol dehydrogenase

1

1

High-throughput

0.437

High

95203

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.426

High

356729

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

0

High-throughput

0.426

High

782692

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

0

High-throughput

0.426

High

786360

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

1

0

High-throughput

0.426

High

823743

SQH
Myosin regulatory light chain sqh

1

0

High-throughput

0.426

High

834836

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.426

High

834840

ROP
Protein ROP

1

0

High-throughput

0.426

High

834858

LDH
L-lactate dehydrogenase

1

0

High-throughput

0.426

High

834865

Q9V9Q4
LD43819p

1

0

High-throughput

0.426

High

834877

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.426

High

834881

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.426

High

834889

Q9W004
Purine nucleoside phosphorylase

1

1

High-throughput

0.417

High

473593

RAS1
Ras-like protein 1

1

3

High-throughput

0.407

High

704332

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.407

High

753184

GLT
Glutactin

1

1

High-throughput

0.407

High

809477

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.407

High

834835

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

834846

Q7K3H0
LD28067p

1

1

High-throughput

0.407

High

834853

Q8SY39
ATP-dependent RNA helicase DDX54

1

4

High-throughput

0.407

High

834855

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

834859

Q960C7
NADP-retinol dehydrogenase

1

1

High-throughput

0.407

High

834861

NOG1
Nucleolar GTP-binding protein 1

1

2

High-throughput

0.407

High

834866

Q9VDK7
Signal recognition particle subunit SRP72

1

2

High-throughput

0.407

High

834867

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

4

High-throughput

0.407

High

834868

Q9VI53
LD44267p

1

1

High-throughput

0.407

High

834869

DDX47
ATP-dependent RNA helicase DDX47

1

3

High-throughput

0.407

High

834878

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.407

High

834879

Q9VT75
N-terminal amino-acid N(alpha)-acetyltransferase NatA

1

1

High-throughput

0.407

High

834882

RS10B
Small ribosomal subunit protein eS10B

1

2

High-throughput

0.407

High

834884

Q9VXK5
Putative rRNA methyltransferase

1

1

High-throughput

0.407

High

834886

Q9VXR5
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.407

High

834887

Q9VZ88
AT07585p

1

2

High-throughput

0.407

High

834892

Q9W414
Regulatory particle triple-A ATPase 4

1

2

High-throughput

0.407

High

834893

Q9W4N8
LD30122p

1

2

High-throughput

0.407

High

834888

Q9VZF5
Kinesin-like protein

2

0

High-throughput

0.298

High

57104

A1ZAU6
FI05912p

1

0

High-throughput

0.265

Low

144859

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.232

Low

264389

O62530
Adaptor protein complex 2, mu subunit, isoform A

1

0

High-throughput

0.232

Low

304187

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

360521

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

654835

MA205
205 kDa microtubule-associated protein

1

0

High-throughput

0.232

Low

715077

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

834832

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

834833

ACTZ
Actin-related protein 1

1

0

High-throughput

0.232

Low

834839

ARL2
ADP-ribosylation factor-like protein 2

1

0

High-throughput

0.232

Low

834842

Q0E9E2
Pyruvate carboxylase

1

0

High-throughput

0.232

Low

834844

Q6NP72
GEO09659p1

1

0

High-throughput

0.232

Low

834845

Q7K161
LD06095p

1

0

High-throughput

0.232

Low

834849

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

0

High-throughput

0.232

Low

834851

Q86BS3
Chromator, isoform A

1

0

High-throughput

0.232

Low

834852

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

834854

Q8SY53
GH11935p

1

0

High-throughput

0.232

Low

834856

Q8T8W3
AT21416p

1

0

High-throughput

0.232

Low

834857

MESD
LDLR chaperone boca

1

0

High-throughput

0.232

Low

834862

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

834863

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

834864

Q9V455
Importin subunit alpha

1

0

High-throughput

0.232

Low

834870

Q9VK57
PIH1 domain-containing protein 1

1

0

High-throughput

0.232

Low

834873

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

834874

Q9VM69
Nucleolar protein 58

1

0

High-throughput

0.232

Low

834876

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.232

Low

834880

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

0

High-throughput

0.232

Low

834883

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

834890

Q9W1H8
acetyl-CoA C-acyltransferase

1

0

High-throughput

0.232

Low

834891

Q9W3N1
RH59310p

1

0

High-throughput

0.232

Low

834894

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025