Protein: TRX1
Thioredoxin-1 (Thioredoxin I) (TR-I) (Thioredoxin-2)

Gene: TRX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P22217

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000139 - Golgi membrane
GO:0000324 - fungal-type vacuole
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646595

TSA1
Peroxiredoxin TSA1

4

20

Small-scale

0.886

High

646584

TRX2
Thioredoxin-2

3

11

Small-scale

0.821

High

613739

MET16
Phosphoadenosine phosphosulfate reductase

1

1

Small-scale

0.751

High

646597

AHP1
Peroxiredoxin AHP1

1

6

Small-scale

0.751

High

646602

MSRA
Peptide methionine sulfoxide reductase

1

5

Small-scale

0.656

High

486035

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.618

High

646585

SIS1
Protein SIS1

1

1

High-throughput

0.618

High

646611

NOP3
Serine/arginine

1

2

High-throughput

0.618

High

646617

TSA2
Peroxiredoxin TSA2

1

20

High-throughput

0.618

High

616384

SEC18
Vesicular-fusion protein SEC18

2

11

Small-scale

0.595

High

578865

HSC82
ATP-dependent molecular chaperone HSC82

2

8

High-throughput

0.584

High

646589

TRXB1
Thioredoxin reductase 1

1

14

Small-scale

0.575

High

646621

RIX7
Ribosome biogenesis ATPase RIX7

1

10

High-throughput

0.536

High

632613

DBP4
ATP-dependent RNA helicase HCA4

1

1

High-throughput

0.515

High

646591

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

2

High-throughput

0.515

High

646604

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

2

High-throughput

0.515

High

646618

GLO2
Hydroxyacylglutathione hydrolase, cytoplasmic isozyme

1

1

High-throughput

0.515

High

646628

GST2
Glutathione S-transferase 2

1

10

High-throughput

0.515

High

437879

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

646614

ERO1
Endoplasmic oxidoreductin-1

1

6

Small-scale

0.501

High

646619

KYNU
Kynureninase

1

0

High-throughput

0.493

High

646613

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.481

High

646610

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

Small-scale

0.480

High

364335

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.479

High

364932

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

392243

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.479

High

434836

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

458531

SEC4
Ras-related protein SEC4

1

3

High-throughput

0.479

High

502855

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

514462

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

543842

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.479

High

638703

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

1

High-throughput

0.479

High

646586

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

646587

CDC48
Cell division control protein 48

1

10

High-throughput

0.479

High

646588

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

646592

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

646593

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

646594

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

646596

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.479

High

646598

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.479

High

646599

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

646600

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

646601

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

646605

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

646606

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

646607

MOG1
Nuclear import protein MOG1

1

2

High-throughput

0.479

High

646609

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

646612

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

646616

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

646622

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.479

High

646624

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

646625

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

646626

VAM3
Syntaxin VAM3

1

2

Small-scale

0.479

High

367226

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

441712

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

512263

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

512826

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

594190

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

646590

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

646608

BPL1
Biotin--protein ligase

1

0

High-throughput

0.458

High

646627

NYV1
Vacuolar v-SNARE NYV1

1

0

Small-scale

0.458

High

646615

RLI1
Translation initiation factor RLI1

1

2

Small-scale

0.457

High

358116

ADH1
Alcohol dehydrogenase 1

1

2

Small-scale

0.445

High

359149

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

10

Small-scale

0.445

High

453897

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.445

High

646603

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

646620

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

646623

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

597384

EF3A
Elongation factor 3A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025