Protein: VAC8
Vacuolar protein 8

Gene: VAC8
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P39968

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000045 - autophagosome assembly
GO:0000329 - fungal-type vacuole membrane
GO:0000407 - phagophore assembly site
GO:0000425 - pexophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

765781

VAC8
Vacuolar protein 8

4

14

Small-scale

0.908

High

765822

ATG13
Autophagy-related protein 13

9

0

Small-scale

0.726

High

756727

NVJ1
Nucleus-vacuole junction protein 1

6

0

Small-scale

0.712

High

634913

VAC17
vacuole-related protein 17

4

0

Small-scale

0.677

High

765788

PFA3
Palmitoyltransferase PFA3

3

1

Small-scale

0.651

High

765810

RAGAB
GTP-binding protein GTR1

2

1

High-throughput

0.608

High

731046

YKT6
Synaptobrevin homolog YKT6

2

1

Small-scale

0.602

High

543793

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

765824

LAM6
Membrane-anchored lipid-binding protein LAM6

2

0

Small-scale

0.569

High

765826

TCO89
Target of rapamycin complex 1 subunit TCO89

2

0

Small-scale

0.569

High

765828

VAM3
Syntaxin VAM3

1

5

Small-scale

0.561

High

757902

ATC2
Calcium-transporting ATPase 2

1

2

High-throughput

0.541

High

765798

IML1
Vacuolar membrane-associated protein IML1

1

6

High-throughput

0.541

High

765818

DPP1
Diacylglycerol pyrophosphate phosphatase 1

1

1

High-throughput

0.541

High

765832

ATG11
Autophagy-related protein 11

1

0

Small-scale

0.537

High

691807

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.536

High

765801

ATG1
Serine/threonine-protein kinase ATG1

1

9

Small-scale

0.536

High

536691

SNA3
Protein SNA3

1

0

High-throughput

0.518

High

698287

COT1
Vacuolar zinc transporter COT1

1

0

High-throughput

0.518

High

728870

OSH1
Oxysterol-binding protein homolog 1

1

0

High-throughput

0.518

High

748235

FTH1
Iron transporter FTH1

1

0

High-throughput

0.518

High

761569

VATF
V-type proton ATPase subunit F

1

0

High-throughput

0.518

High

765812

MEH1
Protein MEH1

1

0

High-throughput

0.518

High

765823

SNA4
Protein SNA4

1

0

High-throughput

0.518

High

765808

ACT
Actin

1

10

Small-scale

0.515

High

690445

HXT1
Low-affinity glucose transporter HXT1

1

1

High-throughput

0.494

High

765797

JSN1
Protein JSN1

1

1

High-throughput

0.494

High

765785

RFC2
Replication factor C subunit 2

1

1

High-throughput

0.489

High

765805

BUD32
EKC/KEOPS complex subunit BUD32

1

0

Small-scale

0.486

High

765811

ACAC
Acetyl-CoA carboxylase

1

2

Small-scale

0.481

High

366339

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

606273

VPS15
Serine/threonine-protein kinase VPS15

1

7

High-throughput

0.479

High

608963

VPS34
Phosphatidylinositol 3-kinase VPS34

1

6

High-throughput

0.479

High

628090

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

630603

ADP1
Probable ATP-dependent permease

1

1

High-throughput

0.479

High

648984

PHO91
Low-affinity phosphate transporter PHO91

1

1

High-throughput

0.479

High

680731

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

715193

TOR1
Serine/threonine-protein kinase TOR1

1

9

High-throughput

0.479

High

746905

PFF1
Vacuolar membrane protease

1

1

High-throughput

0.479

High

747346

PHO88
SRP-independent targeting protein 3

1

1

Small-scale

0.479

High

765678

KC13
Casein kinase I homolog 3

1

17

High-throughput

0.479

High

765783

VTC1
Vacuolar transporter chaperone complex subunit 1

1

3

High-throughput

0.479

High

765787

SYG1
Protein SYG1

1

1

High-throughput

0.479

High

765790

VTC2
Vacuolar transporter chaperone complex subunit 2

1

4

High-throughput

0.479

High

765791

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

10

High-throughput

0.479

High

765793

RMD8
Sporulation protein RMD8

1

1

High-throughput

0.479

High

765796

VTC4
Vacuolar transporter chaperone complex subunit 4

1

4

High-throughput

0.479

High

765799

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

765813

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

4

High-throughput

0.479

High

765815

RMD1
Sporulation protein RMD1

1

1

High-throughput

0.479

High

765816

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

765825

MCA1
Metacaspase-1

1

1

High-throughput

0.479

High

765829

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.479

High

765833

YPK9
Vacuolar cation-transporting ATPase YPK9

1

3

High-throughput

0.479

High

765792

YFK5
Uncharacterized protein YFR035C

1

0

Small-scale

0.460

High

513496

PPB
Repressible alkaline phosphatase

1

0

High-throughput

0.458

High

605436

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.458

High

688983

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.458

High

693208

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.458

High

700915

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

747580

ATG14
Autophagy-related protein 14

1

0

Small-scale

0.458

High

765789

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

0

High-throughput

0.458

High

765814

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

765817

VTI1
t-SNARE VTI1

1

0

Small-scale

0.458

High

765831

YVC1
Calcium channel YVC1

1

0

High-throughput

0.458

High

765820

ERFB
Palmitoyltransferase ERF2

1

2

Small-scale

0.457

High

765804

RAGCD
GTP-binding protein GTR2

1

1

High-throughput

0.457

High

491320

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

494046

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

511421

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

585319

MYO2
Myosin-2

1

5

Small-scale

0.445

High

339655

CDK1
Cyclin-dependent kinase 1

1

9

High-throughput

0.437

High

478231

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.437

High

662308

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

765806

HST2
NAD-dependent protein deacetylase HST2

1

12

High-throughput

0.437

High

765809

H3
Histone H3

1

9

High-throughput

0.437

High

765827

NCE2
Non-classical export protein 2

1

0

High-throughput

0.426

High

765830

PRR2
Serine/threonine-protein kinase PRR2

1

11

High-throughput

0.417

High

765795

JJJ2
J protein JJJ2

1

1

High-throughput

0.407

High

765782

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

4

0

Small-scale

0.360

High

765784

LDO16
Lipid droplet organization protein LDO16

2

0

Small-scale

0.310

High

765807

FMP41
Uncharacterized mitochondrial hydrolase FMP41

1

0

High-throughput

0.269

Low

474351

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

696969

YEF3
Uncharacterized protein YEL043W

1

0

Small-scale

0.251

Low

765786

TAO3
Cell morphogenesis protein PAG1

1

0

Small-scale

0.251

Low

765819

EAF1
Chromatin modification-related protein EAF1

1

0

Small-scale

0.251

Low

357286

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

701445

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

765800

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

765803

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.249

Low

728109

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.238

Low

765802

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.238

Low

765821

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.238

Low

765794

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024