HitPredict

Interactor 1: PGTB2 (P20133)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Type II protein geranyl-geranyltransferase subunit beta) (PGGT) (YPT1/SEC4 proteins geranylgeranyltransferase subunit beta)
Gene: BET2

Interactor 2: PGTA (Q00618)
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (GGTase-II-alpha) (Geranylgeranyl transferase type II subunit alpha) (PGGT) (Type II protein geranyl-geranyltransferase subunit alpha) (YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha)
Gene: BET4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 8756702, 11805826, 40049413, 18719252, 16429126
Identification Methods biochemical, tandem affinity purification, affinity chromatography technology, two hybrid
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PPTA~Prenyltrans
Common GO terms GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005829 - cytosol
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0006612 - protein targeting to membrane
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 325
Sc

1 327
+ Rn
+ Hs
+ Dm
+ Hs
+ Rn
+ Ce
+ Dm
+ Ce
+ Hs
+ Rn
+ Hs
+ At
+ Sc
+ Hs
+ Sp
+ Dm
+ Dm
+ Sc
+ Sp
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025