Interactor 1: MSH3 (P25336)
DNA mismatch repair protein MSH3 (Mismatch-binding protein) (MBP) (MutS protein homolog 3)
Gene: MSH3

Interactor 2: MSH6 (Q03834)
DNA mismatch repair protein MSH6 (MutS protein homolog 6) (Postmeiotic segregation protein 3)
Gene: MSH6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 8600025, 11805826, 16429126
Identification Methods coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MutS_I~MutS_I, MutS_I~MutS_II, MutS_I~MutS_III, MutS_I~MutS_V, MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V
Common GO terms GO:0000710 - meiotic mismatch repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006298 - mismatch repair
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1018
Sc

1 1242
+ Sc
+ Hs
+ Mm
+ Dr
+ Hs
+ At
+ Hs
+ At
+ Ec
+ Sc
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024