HitPredict

Interactor 1: PRVA (P20472)
Parvalbumin alpha (Alpha-parvalbumin) (Alpha-PV)
Gene: PVALB

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~EF-hand_7, EF-hand_7~EFhand_Ca_insen, EF-hand_7~Spectrin
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 110 Hs			1 2472
+	Hs
		516514 CALM3_HUMAN (43-109): 2.67e-16: 71.3: 29.85		SPTN1_HUMAN (1-2472): 0: 707: 100.00
+	Ce
		109082 CALM_CAEEL (43-109): 3.8e-16: 70.9: 29.85		G4S034_CAEEL (4-2472): 3.39e-163: 564: 57.91
+	Dm
		561566 CALM_DROME (43-109): 3.8e-16: 70.9: 29.85		SPTCA_DROME (2-2202): 1.51e-76: 286: 23.12
+	Dm
		612368 CALM_DROME (43-109): 3.8e-16: 70.9: 29.85		ACTN_DROME (1864-2470): 1.19e-77: 281: 30.27
+	Hs
		516503 CALM3_HUMAN (43-109): 2.67e-16: 71.3: 29.85		SPTB2_HUMAN (756-2418): 1.66e-38: 161: 16.65
+	Hs
		176931 CALM2_HUMAN (43-109): 2.67e-16: 71.3: 29.85		CE290_HUMAN (1016-2421): 2.61e-29: 131: 9.59
+	Hs
		176932 CALM3_HUMAN (43-109): 2.67e-16: 71.3: 29.85		CE290_HUMAN (1016-2421): 2.61e-29: 131: 9.59
+	Hs
		224592 CALM3_HUMAN (43-109): 2.67e-16: 71.3: 29.85		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15