HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 156
+	Hs
		893645 PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		638108 PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		637386 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Mm
		477050 PSA1_MOUSE (1-263): 2.54e-109: 317: 98.10		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		576260 PSA1_RAT (1-263): 2.14e-108: 315: 97.72		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		656197 PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		893646 PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	At
		189234 PSA7B_ARATH (4-233): 4.98e-96: 283: 32.34		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Rn
		893780 PSA6_RAT (1-240): 1.64e-92: 274: 25.00		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	At
		188704 PSA1B_ARATH (1-240): 1.35e-94: 280: 50.00		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		709289 PSA1A_ARATH (1-238): 1.05e-93: 278: 50.00		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		188696 PSA2A_ARATH (1-237): 1.71e-93: 276: 32.64		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		1091773 PSA2B_ARATH (1-237): 1.1e-92: 274: 32.64		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		286456 PSA4A_ARATH (1-245): 1.92e-91: 272: 28.85		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		286449 PSA6A_ARATH (1-240): 4.34e-91: 270: 29.03		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474931 PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		672527 PSA7A_ARATH (5-218): 8.98e-37: 132: 35.32		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81