HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: BACD1 (Q8WZ19)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein)
Gene: KCTD13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 329
+	Hs
		637413 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		BACD2_HUMAN (23-329): 7.29e-132: 379: 64.50
+	Hs
		637462 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		KCTD1_HUMAN (16-265): 1.65e-56: 185: 20.15
+	Hs
		637521 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		KCTD7_HUMAN (3-176): 2.07e-41: 147: 31.64
+	Hs
		637484 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		KCD17_HUMAN (41-192): 1.02e-40: 146: 28.93
+	Hs
		637488 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		KCTD6_HUMAN (40-215): 1.51e-41: 146: 28.25
+	Hs
		637463 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		KCTD9_HUMAN (14-166): 7.06e-35: 132: 33.33
+	Ce
		954555 PSA7_CAEEL (4-217): 6.66e-36: 130: 34.10		P91563_CAEEL (40-211): 6e-47: 160: 31.61
+	Ce
		109386 PSA7_CAEEL (4-217): 6.66e-36: 130: 34.10		H2KY83_CAEEL (39-226): 5.22e-46: 156: 27.66
+	Ce
		1090315 PSA7_CAEEL (4-217): 6.66e-36: 130: 34.10		Q18776_CAEEL (26-192): 1.06e-42: 150: 24.43