HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 35271311, 19193609
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 234 Hs			1 271
+	Hs
		656281 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893716 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		156330 PSA7_HUMAN (6-231): 1.49e-89: 266: 36.52		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		637501 PSA1_HUMAN (1-233): 1.31e-89: 266: 30.67		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		638170 PSA4_HUMAN (4-211): 1.24e-42: 146: 38.68		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893684 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		Q5QPM9_HUMAN (1-183): 1.97e-104: 302: 100.00