Interactor 1: PAX6 (P26367)
Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
Gene: PAX6
Interactor 2: CDX2 (Q99626)
Homeobox protein CDX-2 (CDX-3) (Caudal-type homeobox protein 2)
Gene: CDX2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.52 | 1.00 | 0.724 |
The method score is based on:
Property | Details |
---|---|
Experiments | 10506141 |
Identification Methods | pull down, affinity chromatography technology |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Homeodomain~Homeodomain |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific and 8 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024