HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043410 - positive regulation of MAPK cascade GO:0043495 - protein-membrane adaptor activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 161
+	Hs
		348729 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		350256 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		918888 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1152088 RAB1B_HUMAN (4-186): 2.6e-74: 223: 31.44		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		914141 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00