Protein: ITA2B
Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]

Gene: ITA2B, ITGA2B
Organism: Homo sapiens
Interactions: 27
UniProt ID: P08514

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002687 - positive regulation of leukocyte migration
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

423998

ITB3
Integrin beta-3

16

20

Small-scale

0.987

High

470417

ITA2B
Integrin alpha-IIb

3

3

Small-scale

0.872

High

470421

FLNA
Filamin-A

1

3

Small-scale

0.692

High

470428

CIB1
Calcium and integrin-binding protein 1

2

2

Small-scale

0.606

High

470431

RN181
E3 ubiquitin-protein ligase RNF181

2

1

Small-scale

0.575

High

470433

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.573

High

470425

ICLN
Methylosome subunit pICln

1

0

Small-scale

0.537

High

470429

SHRPN
Sharpin

1

7

Small-scale

0.512

High

366089

THRB
Prothrombin

1

6

Small-scale

0.501

High

384232

CO2A1
Collagen alpha-1(II) chain

1

5

Small-scale

0.501

High

388923

FINC
Fibronectin

1

6

Small-scale

0.501

High

399527

VTNC
Vitronectin

1

5

Small-scale

0.501

High

407750

VWF
von Willebrand factor

1

3

Small-scale

0.501

High

421342

A4
Amyloid-beta precursor protein

1

4

Small-scale

0.501

High

470420

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.501

High

470426

GRB2
Growth factor receptor-bound protein 2

1

7

Small-scale

0.501

High

470432

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

Small-scale

0.480

High

470418

CD36
Platelet glycoprotein 4

1

1

Small-scale

0.479

High

470424

EFNA4
Ephrin-A4

1

3

High-throughput

0.479

High

470419

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

470423

PA24A
Cytosolic phospholipase A2

1

2

Small-scale

0.457

High

470427

CD177
CD177 antigen

1

4

Small-scale

0.445

High

470430

FBX6
F-box only protein 6

1

11

High-throughput

0.437

High

387691

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

5

Small-scale

0.408

High

387939

FIBG
Fibrinogen gamma chain

1

5

Small-scale

0.408

High

470422

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025