HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: SLA2 (P33338)
Protein SLA2 (Transmembrane protein MOP2)
Gene: SLA2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	12181333, 18467557, 37968396
Identification Methods	two hybrid, protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0032051 - clathrin light chain binding GO:0048268 - clathrin coat assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 968
+	Hs
		157248 CLH1_HUMAN (4-1648): 0: 2877: 49.76		CTRO_HUMAN (216-968): 2.5e-72: 264: 14.38
+	Hs
		130942 CLH1_HUMAN (4-1648): 0: 2877: 49.76		HIP1_HUMAN (4-965): 2.27e-61: 228: 18.85
+	Hs
		271698 CLH1_HUMAN (4-1648): 0: 2877: 49.76		HIP1R_HUMAN (3-962): 5.54e-59: 222: 19.98
+	Hs
		252758 CLH1_HUMAN (4-1648): 0: 2877: 49.76		AP180_HUMAN (6-276): 2.01e-56: 212: 15.71
+	Hs
		1026016 CLH1_HUMAN (4-1648): 0: 2877: 49.76		PICAL_HUMAN (6-331): 2.77e-54: 202: 13.99
+	Hs
		157131 CLH2_HUMAN (4-1635): 0: 2756: 48.90		CTRO_HUMAN (216-968): 2.5e-72: 264: 14.38
+	Hs
		130929 CLH2_HUMAN (4-1635): 0: 2756: 48.90		HIP1_HUMAN (4-965): 2.27e-61: 228: 18.85
+	Hs
		252755 CLH2_HUMAN (4-1635): 0: 2756: 48.90		AP180_HUMAN (6-276): 2.01e-56: 212: 15.71
+	Hs
		922428 CLH2_HUMAN (4-1635): 0: 2756: 48.90		PICAL_HUMAN (6-331): 2.77e-54: 202: 13.99
+	Hs
		1026156 CLH1_HUMAN (4-1648): 0: 2877: 49.76		MY18A_HUMAN (338-781): 3.04e-11: 70: 14.38
+	At
		1081958 CLAH1_ARATH (2-1642): 0: 2625: 43.39		AP180_ARATH (6-325): 7.18e-52: 195: 14.84