HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: LYST (Q99698)
Lysosomal-trafficking regulator (Beige homolog)
Gene: LYST

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	11984006, 36931259
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 3801
+	Hs
		909956 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		927452 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		683662 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		684291 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		982423 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		905035 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		LYST_HUMAN (1-3801): 0: 5885: 100.00
+	Hs
		910139 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FBW1B_HUMAN (3301-3799): 6.14e-82: 283: 14.37
+	Hs
		910177 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		927638 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FBW1B_HUMAN (3301-3799): 6.14e-82: 283: 14.37
+	Hs
		647395 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		683802 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FBW1B_HUMAN (3301-3799): 6.14e-82: 283: 14.37
+	Hs
		927675 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		683828 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FBW1A_HUMAN (3302-3799): 6.55e-79: 277: 13.75
+	Hs
		792954 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LIS1_HUMAN (3595-3801): 9.94e-51: 188: 15.71
+	Hs
		792963 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LIS1_HUMAN (3595-3801): 9.94e-51: 188: 15.71
+	Hs
		683188 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		LIS1_HUMAN (3595-3801): 9.94e-51: 188: 15.71
+	Hs
		903106 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		WDR5_HUMAN (3695-3799): 3.08e-24: 109: 20.00
+	Hs
		792974 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		LIS1_HUMAN (3595-3801): 9.94e-51: 188: 15.71
+	Hs
		792950 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		LIS1_HUMAN (3595-3801): 9.94e-51: 188: 15.71
+	Hs
		927195 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NBEL2_HUMAN (3662-3801): 3.8e-12: 75.5: 12.99