HitPredict

Interactor 1: NDKB (P22392)
Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2)
Gene: NME2

Interactor 2: NDKB (P22392)
Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2)
Gene: NME2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 31980649, 7658474, 33961781, 31839598, 38096103, 21988832
Identification Methods affinity chromatography technology, x-ray crystallography, cross-linking study, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NDK~NDK
Common GO terms GO:0001726 - ruffle
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0004550 - nucleoside diphosphate kinase activity
GO:0004673 - protein histidine kinase activity
and 27 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 152
Hs

1 152
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Service provided by Combinatics, Japan

Last updated: 11Aug2025