HitPredict

Interactor 1: ENPP1 (P22413)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Alkaline phosphodiesterase I) (EC 3.1.4.1) (Membrane component chromosome 6 surface marker 1) (Nucleotide diphosphatase) (Nucleotide pyrophosphatase) (NPPase) (EC 3.6.1.9) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form]
Gene: ENPP1

Interactor 2: S39A4 (Q6P5W5)
Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4)
Gene: SLC39A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 925 Hs			1 647
+	Hs
		648283 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39AC_HUMAN (20-645): 0: 541: 31.11
+	Hs
		648278 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39AE_HUMAN (201-645): 2.06e-106: 332: 29.35
+	Hs
		648309 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39A8_HUMAN (205-645): 1.1e-88: 285: 28.60
+	Hs
		648299 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39A7_HUMAN (310-642): 4.54e-70: 237: 28.01
+	Hs
		648305 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39AD_HUMAN (285-643): 9.11e-65: 219: 25.73
+	Hs
		648293 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39AB_HUMAN (330-640): 3.63e-48: 174: 19.76
+	Hs
		648317 ENPP1_HUMAN (1-925): 0: 1364: 100.00		S39A1_HUMAN (361-638): 2.85e-37: 143: 17.54
+	Hs
		1242881 PIGO_HUMAN (211-433): 2.48e-50: 194: 15.35		S39A4_HUMAN (23-647): 0: 604: 100.00
+	Hs
		336540 PIGN_HUMAN (200-447): 7.35e-55: 208: 15.73		S39AE_HUMAN (201-645): 2.06e-106: 332: 29.35