HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 411
+	Hs
		650824 RFA1_HUMAN (1-616): 0: 781: 100.00		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		651186 RFA1_HUMAN (1-616): 0: 781: 100.00		IF4A2_HUMAN (20-411): 4.07e-177: 501: 69.47
+	Hs
		571319 RFA1_HUMAN (1-616): 0: 781: 100.00		DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63
+	Hs
		651854 RFA1_HUMAN (1-616): 0: 781: 100.00		DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79
+	Hs
		133889 RFA1_HUMAN (1-616): 0: 781: 100.00		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		640331 RFA1_HUMAN (1-616): 0: 781: 100.00		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83